In the most luxurious hotel suites, including a luxury restaurant, a private swimming pool with hot springs, and two kitchens for cooking Asian and European delicacies, guests can book dishes at any time. The room rate of $5,000 per night does not include the service charge. In MGM Hotel, the smallest suite area is about 260 square meters, and the largest is over 800 square meters. The room rate in the most luxurious room is as high as $15,000 per night.

NO.2: Seychelles North Island Hotel

Located on the North Island of Seychelles.

Seychelles is an unknown island country on the east coast of Africa, but it has two most expensive hotels in the world. The location of North Island Hotel is a famous tourist attraction in Seychelles, and the basic fee of the hotel includes all the catering expenses of the residents. Each villa in the hotel is completely built by local craftsmen, and the smallest one has an area of 440 square meters. Each villa is equipped with 2 bedrooms, indoor air conditioning, broadband, satellite TV and so on. Most of the food provided by the hotel comes from local botanical gardens and farms.

NO.3: Freguet Island Hotel

Located in Fregete Island, Seychelles.

Fregete Island is a tourist attraction in Seychelles, which is privately owned by German industrialist Othaber. This resort has only 16 suites and can only accommodate up to 40 guests. Each suite includes 2 bedrooms, 1 massage room, 1 solarium and 2 ordinary bathrooms, one of which is open, lying in the bathtub and enjoying the beautiful scenery of nature.

The air ticket from Mayi, the main island of Seychelles, to Fregete Island is also very expensive. In the tourist season, the price of an air ticket is as high as 2000 US dollars.

NO.4: French Guadeloupe Hotel

Located in the French West Indies

This manor castle hotel consists of 14 one-bedroom cabins and a three-bedroom cabin, which is built behind the traditional French plantation. Each cabin is equipped with a mahogany queen bed and swimming pool, and the room price of $2,092 includes breakfast and free airport transfer.

NO.5: Xinjita Private Animal Reserve

Located in Sabisand, South Africa

This private animal sanctuary covers an area of 19,000 hectares, and the room rate includes two tours in the sanctuary every day, shuttle service from the airport to the hotel, unlimited drinks and free washing and ironing services for clothes. Guests can choose their own residence in 18 suites in 5 courtyards, and they can also enjoy 12,000 bottles of local fine wines collected in the wine cellar of the hotel. Although the room rate is more expensive than Guadeloupe Hotel, it ranks fifth because of the rich services included with the accommodation.

NO.6: wakaya club

Located in Fiji, a Pacific island country

The fee of Vakaya Club in Fiji, which has beautiful gardens, is quite amazing, and the club stipulates that guests staying here must stay for at least 5 days! The room rate includes all meals, clothing cleaning, free guidance from golf and tennis coaches, where guests can play croquet, canoe and dive twice a day.

NO.7: Turtle Island Hotel

Located in Fiji

The hotel has 14 double suites, each of which is made of thatch and the roof is arched. Every suite in the hotel has a balcony with sea view and a jetted jacuzzi. The room rate includes all meals and activities (such as deep-sea fishing and ocean)

　The sauna center men’s locker room is equipped with a camera, claiming to protect the safety of customers’ property.

　　　　What do you think when you change clothes in the locker room of sauna center and suddenly find a camera on it? On August 31, Mr. Wang reported to the Times that the Longx Sauna Leisure Center in Xiqiao Road, Baiyun District actually installed camera monitoring in the locker room, but did not inform in advance, and violated the right to privacy. However, the person in charge of the sauna center replied that they were considering from the perspective of guests to prevent people from stealing property.

　　　　Information: the locker room is equipped with a camera.

　　　　Mr. Wang works as a department manager in a company in Guangzhou. On August 31st, he led several clients to the Dragon X Sauna Center near Ezhutan, Xicha Road, Baiyun District for sauna and business talks. Mr. Wang washed quickly, so he went to the dressing room to wait for the customer, and was ready to get dressed and go to the lounge. When he looked up, he found that there was a camera in the middle of the main wall of the dressing room, and he felt that his privacy was violated. He went to the manager on duty in the sauna center to ask for a statement.

　　　　"I wanted to take a shower and feel comfortable, but I didn’t expect to encounter embarrassing things. How can the sauna center install cameras in the locker room, and everyone will see them? Too embarrassed! " Seeing the reporter, Mr. Wang was upset and thought that the sauna center was a bit outrageous. At that time, Mr. Wang also went to the camera and looked at it. "The monitor is still on!"

　　　　Scene: the guest locker room was photographed naked.

　　　　Yesterday afternoon, the reporter came to the sauna leisure center next to the goose’s paw temple number on Xicha Road on the grounds of sauna. Guided by the consultant in the lobby, the reporter and his party entered the dressing room of sauna center. The dressing room is small, about 13 square meters, with a camera on each wall and a cabinet for guests to store their belongings and clothes below.

　　　　At that time, the reporter raised an objection, claiming that guests would be photographed naked when they changed clothes. The waiter replied that the camera is mainly to monitor the locker room, and it will definitely shoot the naked body, but as long as the guest wraps his lower body with a bath towel, he will not shoot the private part.

　　　　Merchant: The camera is only installed for theft prevention.

　　　　Why is monitoring equipment installed in the locker room? The manager on duty in the lobby of the sauna center told the reporter that they were for safety reasons. In order to prevent theft, "monitoring equipment is installed to prevent criminals from stealing guests’ property. The filming content does not involve the process of massage and dressing."

　　　　However, when the reporter questioned that the dressing room screen could see the naked scene of the guests, the manager was speechless, and then prevaricated on the grounds that "the boss is not here, and these questions are not easy to answer".

　　　　Lawyer: You can call the police if you find that you have been photographed.

　　　　Mr. Wang said that no matter which angle the sauna center considers, it will definitely violate the privacy of the guests. "If these nude photos are posted online, wouldn’t it be a shame?" Like Mr. Wang, there are six or seven citizens, such as Mr. Duan and Mr. Zhang, who all oppose the installation of cameras in the dressing room of the sauna center and should strengthen their own safety and security.

　　　　Regarding the practice of installing cameras in the dressing room in the sauna center on the grounds of safety and anti-theft, lawyer Xiao Xionghui of Guangdong Shunhua Law Firm said that installing cameras in the dressing room to photograph the naked bodies of others is beyond the allowable limit for monitoring public safety and is suspected of infringing on the privacy of others. There is nothing wrong with installing monitoring equipment in sauna center for safety reasons without involving customers’ privacy, but installing and using it in dressing room is an infringement. Specifically, it is an infringement of customers’ privacy.

　　　　Police: Installation of security equipment requires approval.

　　　　Guangzhou police said that the installation of monitoring equipment in the dressing room of sauna center needs the permission and approval of relevant departments. Once the surveillance image leaks and causes reputational damage to others, the victim has the right to claim compensation. It is understood that according to the relevant laws and regulations: "Anyone who has one of the acts of voyeurism, sneak shot, eavesdropping or spreading the privacy of others shall be detained for less than 5 days or fined for less than 500 yuan; If the circumstances are serious, they shall be detained for more than 5 days and less than 10 days, and may be fined up to 500 yuan. "

　　　　In recent years, China’s legislation on voyeurism and sneak shots (including mobile phone sneak shots) has been strengthened. If a party is photographed in a public place, the sneak shot can be ordered to delete photos and videos, and if it is rejected, it can call 110.

Editor: Tian Shijia

Kawasaki motorcycles can be divided into Ninja series, Z series, VERSYS series, Vulcan series, W series and KLX series, and their prices are as follows:

Ninja series

Kawasaki ninja 400

49800-50800 yuan

Kawasaki ninja 650

80800-82300 yuan

Kawasaki ninja ZX-10R

236800-349800 yuan

Kawasaki ninja H2SX

277,000 yuan

Kawasaki ninja H2

424,000 yuan

Kawasaki ninja 1000SX

179,200 yuan

Kawasaki ninja belongs to the sports car series. This model not only looks cool, but also has very strong dynamic performance. Among them, Ninja 400 has become the first choice for many motorcyclists because of its relatively low price. However, this model is uncomfortable in sitting position, and the body steering flexibility is not high enough, which is not suitable for long-distance driving.

Z series

Kawasaki Z400

47,800 yuan

Kawasaki Z650

77,600 yuan

Kawasaki Z900RS

139000-141000 yuan

Kawasaki Z900

107,900 yuan

Kawasaki Z1000

154,000-169,000 yuan

Kawasaki ZH2

239,000 to 269,000 yuan

Kawasaki Z series is a tram. Although the appearance of this model is not as domineering as the ninja series, it is more practical. The height of the seat and pedal of the vehicle is relatively low, and it has a relatively high handle, which can bring better comfort experience to the driver, is more suitable for novice drivers, and is not easy to feel tired even after running for a long distance.

VERSYS series

Kawasaki Versys-X300

47500-52900 yuan

Kawasaki Versys650

85,500 yuan

Kawasaki Versys1000

159,000 yuan

Kawasaki VERSYS series is also called trailer. As the name implies, trailer needs a long endurance, and VERSYS also has a multi-purpose meaning in Kawasaki’s automobile series. Therefore, the Versys series models are suitable for motorcyclists who travel long distances, and the vehicles are more comfortable, mobile and reliable.

W series

Kawasaki W800

108,900-115,900 yuan

Kawasaki W series is a retro model. Double barrel mechanical instrument, classic round headlights and integrated cushion are the standard of this car. The whole vehicle creates a strong retro atmosphere, which is very suitable for consumers who pursue individuality or nostalgia. In addition, it is also a good choice to park this car in an online celebrity shop for decoration.

KLX series

Kawasaki KLX230

37,900 yuan

Kawasaki KLX series is an unpaved trailer motorcycle. This kind of motorcycle has the characteristics of light body, strong power and high ground clearance. Among them, off-road tires are used for wheels that are more suitable for mountain climbing, which can easily cope with various complicated road conditions such as deserts, rivers and mountains, and even climbing stairs is only a matter of slightly twisting the throttle.

What is the cheapest motorcycle in Kawasaki?

As can be seen from the above article, the cheapest motorcycle in Kawasaki is "Kawasaki KLX230", which costs 37,900 yuan, but it belongs to off-road motorcycle and is not suitable for daily driving. So when buying a car, don’t decide according to the price of the vehicle, but start from your own needs. If what you want is a handsome contest, then Ninja 400 with a price of 49,800-50,800 yuan is the best choice. 50,000 to 60,000 yuan can get a "girl-picking artifact", but the exhaust sound of this car is rather embarrassing; If you prefer to ride a bike to run mountains, or have certain requirements for the comfort of vehicles, then it is recommended to buy a Kawasaki Z400 with a price of 47,800 yuan. After all, this streetcar was born for Running Broker. If you want to visit other places, or run the Sichuan-Tibet line, then Kawasaki Versys-X300 is recommended, with a price of 47,500-52,900. The multi-functional model can meet your various needs.

The prices of the above-mentioned cars are all around 50,000 yuan, which is the minimum threshold for becoming a "ninja distinguished car owner". Of course, if you still don’t know how to choose, then I suggest going to the local Kawasaki store. After all, there is still a big gap between the real car and the picture.

　　How much is a peace elite Aston Martin? How about Aston Martin? Is it worth starting with? How did Aston Martin get it? Aston Martin, the peace elite, is a newly launched vehicle skin, which is divided into cars and jeeps, so many players want to know how much is a peace elite Aston Martin? The following is a detailed introduction of the price and acquisition method of Aston Martin, a peace elite, for the majority of players by Xiaobian. Don’t miss it for interested players!

　　How much is a peace elite Aston Martin?

　　Aston Martin is obtained through activities, and it also needs to raise 7 stars, which can increase the probability of the best sports car, and directly explode the car keys, so that players can exchange their favorite colors. It also needs to be drawn here, and the cost is not low. Every time it is 6 yuan, it needs to be drawn at least 200 times to get it. Players can always increase the probability, always synthesize it, and unlock 7 stars to get this skin key 100%.

　　The price of the draw is around 1000~2000, which can be basically drawn. Players who can’t draw can find someone else to guarantee the bottom, or buy it directly. The anchor is guaranteed, and friends can be given away. It is also possible for players to buy it directly. It is most convenient for players with bad luck to recommend buying, and find other players to collect it. If they are lucky, they will draw it themselves, which is basically 300 yuan cheaper than other places.

　　Aston Martin, the new carrier skin, is the best-looking sports car, both sports car and SUV. Both models are full marks. The top sports car design looks strong in lines, has a cool shape, and the top sports car design will drive faster.

　　The new skin is extracted through activities, and it is extracted from the Spring Festival activities-the Story of the Heart. Players can extract it for many times, single and ten times, and activate it for many times to unlock it.

Nanchang Evening News

News recommendation reading

Too sudden! The 36-year-old well-known anchor was diagnosed! On April 8, Kweichow Moutai once fell more than 3% in intraday trading, and finally closed down by 2.82%. On April 9, Kweichow Moutai continued to fall. At the same time, the news that the wholesale price (market circulation price) of bulk bottles of Feitian Moutai fell below 2600 yuan in 2024 also attracted market attention.

Did Feitian Maotai fall?

Regarding the rumor that the price of 53-degree/500-ml Feitian Maotai was reduced, the reporter asked a number of liquor recyclers, and all the answers were "down".

"(Loose bottles) were still 2460 yuan/bottle in the morning, and now they are 2400 yuan/bottle. The market is too fast." On the evening of the 8 th, a liquor recycler told Zhongxin Finance, "If you can’t move, you can’t afford the recycling price."

Another liquor recycler replied that Moutai in different years has been falling recently: "Maotai is now falling dozens a day." The lowest quotation given by the recycler is 2350 yuan/bottle.

Data Map: A supermarket in Guizhou Moutai counter. China News Service reporter Lu Mingshe

In addition to the downward trend in the secondary market price, at the sales terminal, the sales price of Maotai is also lower.

The reporter visited a number of liquor stores in Beijing, and the quotations of some liquor stores dropped from 3,280 yuan/bottle to 3,080 yuan/bottle, while those of some liquor stores dropped from 2,980 yuan/bottle to 2,850 yuan/bottle, with the drop ranging from 150-200 yuan, and the lowest quotation was 2,750 yuan/bottle.

"The price of Maotai in liquor has changed relatively quickly. Yesterday it was 3,100 and 3,200, and today it is 2,800 and 2,900." Some wine companies told reporters.

In addition, some liquor recyclers said that Wuliangye may also cut prices. At present, the recycling price of puwu in bulk bottles is between 800-850 yuan/bottle. However, at the sales terminal, the price of Wuliangye did not fall. Some liquor wholesalers said that due to the previous price increase of Wuliangye, the wholesale price of Wuliangye bulk bottles was slightly raised to 990 yuan/bottle.

On April 9, Kweichow Moutai continued to fall, closing at 1662.22 yuan, down 0.27%.

Why did it fall?

April was originally the off-season of liquor sales, so it seems not unusual for liquor prices to go down. However, in the eyes of many recyclers, the price drop of Maotai this time is unusual. "This is a plunge, not just because of the off-season. If there is wine, either sell it quickly or wait until the Mid-Autumn Festival to see the market. "

The reporter noted that it is generally believed in the industry that the heavy volume of 375ml Xunfeng wine has had an impact on the market of Feitian Maotai.

On December 31, 2023, Maotai officially launched 375ml "Guizhou Maotai Xunfeng Liquor". Maotai officially claimed that this is a strategic product independently developed by Maotai. On March 28th this year, WeChat official account, the WeChat of Xunfeng Digital World, announced that from now on, users who hold relevant materials in the APP can follow the corresponding steps to synthesize the corresponding materials and complete the exercise right, and can complete the delivery of 375ml Kweichow Moutai (Xunfeng) in the online store.

On December 31, 2023, Maotai officially launched 375ml of "Kweichow Moutai Xunfeng Liquor". Screenshot from Kweichow Moutai official WeChat WeChat official account.

Cai Xuefei, a wine commentator and analyst, said: "The decline in the price of famous wines is not only due to the normal off-season of the market, but also related to factors such as the large social inventory in the early stage. In addition, the concentration of Feitian Maotai by individual sellers with large inventory of Maotai and the concentration of 375ml Maotai Xiefeng liquor caused panic in the market, which also caused a short-term decline in the price of Maotai. As a whole, the short-term supply in the market exceeded the demand, which naturally brought price fluctuations. "

Cai Xuefei believes that as a representative of high-end famous liquor, the price decline of Moutai will inevitably lead to the decline of the overall high-end product price in the short term, further squeezing the high-end liquor consumption market and intensifying the competition in the high-end liquor market.

On the afternoon of April 8, insiders of Kweichow Moutai told the media that the planned amount of Xunfeng liquor accounts for a small proportion of the annual amount of Moutai, which will not affect the existing price system of Moutai. At present, the sales of Moutai are in good condition.

Will the price of Maotai warm up?

As for the drop in the price of Maotai, some people think that even if it rises later, it will be difficult to reach the original height. So, will the price of Maotai warm up?

Cai Xuefei believes that although the price of Maotai has fallen in the short term, it will remain strong in the future. "From a rational point of view, the people’s livelihood needs of Maotai in the banquet, business and gift markets have not changed. With the continuous recovery of social economy and the deepening of some marketing measures of Maotai enterprises, the demand of Feitian Maotai will also enter a recovery cycle in the third quarter, thus stabilizing and rebounding, and the overall price is still in an upward trend."

He pointed out that at present, in 2024, the whole wine industry still faces problems such as high inventory, upside-down price and insufficient demand. The market needs time to digest the capacity expanded in the past few years, and the price needs time to repair, which will still lead to 2024. It will be a difficult year.

Kweichow Moutai displayed in liquor stores. Zuo Yuqing photo

"But on the positive side, wine is a folk product in China. Maotai Wuliangye and other famous wines are just needed in banquets, gifts and other markets. The characteristics of this category have not changed. With the continuous improvement of industrial concentration and the trend of consumption upgrading, these famous wines still have good development prospects."

This month, Kweichow Moutai announced its 2023 financial report. The data shows that in 2023, Kweichow Moutai achieved a total operating income of 150.56 billion yuan, a year-on-year increase of 18.04%; The net profit attributable to shareholders of listed companies was 74.734 billion yuan, a year-on-year increase of 19.16%.

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Original title: "Flying Maotai, plummeting! 》

Read the original text

On July 24th, Xi ‘an, a new media program named "Chinese Star" jointly created by the Chinese-foreign Language Exchange and Cooperation Center of the Ministry of Education and CCTV, was officially launched. Xi ‘an — — In ancient times, it was called Chang ‘an and Haojing, and the capitals of more than ten dynasties were established here in history. Xi ‘an has become one of the cities with the largest number of dynasties in the history of China, and it is also one of the four ancient capitals in the world and the starting point of the ancient Silk Road. In this issue, three guests will go to the ancient city wall, Huimin Street and Longji Green Energy to experience the tolerance, diversity, innovation and development of Xi ‘an.

The ancient city wall is integrated into modern science and technology management.

Three guests came to Yongning Gate, and Wu Chunxian, deputy director of Xi ‘an City Wall Management Committee, briefly introduced the situation of the city wall. Ji Weiren of Britain asked Wu Chun about the protection of the ancient city wall and the influence of protecting the ruins of the city wall on urban planning. At the same time, Gunik of Russia also learned that with the continuous development of science and technology, the management of the ancient city wall has also been integrated with modern management methods. The soil monitor buried in the brick body of the city wall can effectively sense the passenger flow, and through big data analysis, it can always grasp whether the carrying capacity of the city wall is overloaded, so as to achieve the effect of real-time monitoring and protection. Song and Ming in Brazil also learned about the thousand-year history of the ancient city wall in Xi ‘an. The restoration and protection of the ancient city wall by generations has a strong historical and cultural research value and needs continuous research and study. At the same time, many rich cultural exchange activities have been held around the theme of ancient city wall protection, which is also a good way for China to communicate with foreign countries and attract more people to understand the development of modern cities in China.

Huimin Street cuisine is the epitome of diversity and tolerance in Xi ‘an.

In the world structure at that time, the Tang Dynasty was in an extremely "developed" state. Countries all over the world constantly sent envoys to Chang ‘an to study or study abroad, and business activities were also extremely frequent, attracting countless businessmen from Arabia, Persia, Central Asia and other places to gather in the workshop, and settled here, constantly thriving, forming a unique amorous feelings street in Xi ‘an — — Huimin street. The delicious food in Huimin Street is a fine product of historical accumulation and inheritance, and the dazzling array of food is also a life expression of the continuous integration and development of multi-ethnic cultures. Three guests came to this street, which is a representative of cultural integration, to taste all kinds of special food in Xi ‘an and learn about the diverse food culture in China.

Science, technology and environmental protection to create a sustainable development future

Three guests went to Longji Green Energy in Xi ‘an to learn about the development of green energy. The first glass of water I received when I came to Longji was zero-carbon drinking water. Niu Yanyan, president of Longji Green Energy China Distribution, introduced the production process of zero-carbon water to three guests, and also introduced the difference between photovoltaic power and traditional power, the advantages of photovoltaic power, its application in the field of life, and the technological breakthrough in aerospace power supply. Ji Weiren learned from Niu Yanyan’s explanation that at present, the power supply of space stations and satellites is all from solar energy, and the research on photovoltaic power generation is just needed, and the requirements for solar energy conversion rate are getting higher and higher. With the continuous exploration and research of Longji Green Energy, the conversion rate of solar panels used in space has finally reached the global leading level. Song Ming learned that if a photovoltaic power station is built in 1% of the world’s deserts, it can meet the global demand for electricity for human production and life. If 70% of the world’s deserts are used to build photovoltaic power stations, it can absorb all our carbon emissions from the beginning to the present. Gunik believes that with the global climate change and the increasing energy demand, green energy has become an important part of energy policies and development strategies in various countries. As a renewable and environment-friendly energy form, solar photovoltaic power generation has been widely concerned, and it is also an important measure to serve all mankind in the future. As a leader in the domestic photovoltaic industry, Longji Green Energy is constantly exploring and studying how to better improve the conversion of solar energy and reduce carbon emissions, so as to contribute to the realization of carbon neutrality at an early date.

Once Chang ‘an, full of flowers, peace and prosperity left a brilliant page in history; Today’s Xi ‘an is still full of charm. Millennium site protection, scientific and technological innovation and green energy development go hand in hand, creating this unprecedented cross-border city. This is Xi ‘an, a Millennium ancient capital with perfect integration of modern technology and traditional culture.

Chris Lee


LEE JOON GI

LEE JOON GI red carpet sells Meng.

[Click to view the high-definition atlas]The red carpet is charming and backless, and LEE JOON GI sells Meng、　 Backstage Laure Shang wears wig for the elderly.

　　　 On April 7th, the 19th Oriental Billboard Awards Ceremony was held in Shanghai. On the red carpet, stars such as Chris Lee, BiBi Zhou, Wang Feng, Chen Chusheng, Twins, Pin Guan, Tanya Chua, Tiger Hu, Dingdang, Stephy, Xu Song, Li Zhunji, Jiang Yingrong, Liu Xijun, Fu Xinbo, Wang Xiaokun, Xue Zhiqian, Supreme Lihe, and Fruity VC appeared in costumes. This year is the 19th birthday of the Oriental Billboard. On that day, every artist brought his 19-year-old souvenirs to share with fans. Among them, the most eye-catching thing is that all the stars put on their 19-year-old youth costumes and made their debut.　

　　　 The biggest number of fans on the red carpet is Chris Lee, and the "corn" fans are holding high yellow flags and waving flags for their idols. Chris Lee, who appeared in orange sportswear with white slacks, really brought a lot of surprises to fans, and she won the All-round Artist Award in one fell swoop that night, which attracted much attention.　

　　　 It is worth mentioning that the appearance of Korean artist LEE JOON GI attracted screams from fans, and LEE JOON GI cordially shook hands with the fans to thank them. As a guest performer, he made his first show in Asia after his retirement that night.

Laure Shang crossed to the age of 91, with white hair and wrinkles.

BiBi Zhou

　　　 Laure Shang, who has always shown people with exaggerated modeling, crossed the age of "91 years old" with white hair and a wrinkled face, once again making Laure Shang the focus of everyone’s attention. BiBi Zhou took off her trademark black-rimmed glasses and wore a blue suit with high heels, which was elegant and handsome. She also won the album of the year award for Akira Kurosawa that night.　

Jiang Yingrong

TWINS

There is a cloud in the synopsis of the golden chamber written by Zhang Zhongjing, a medical sage: "If you eat something, it will harm you, but it will harm you." "If you eat something, it will be suitable for your illness, and it will harm you. If you benefit, it will be suitable for your health, and if it hurts you, it will become a disease." Since ancient times, it is well-known that Chinese medicine pays attention to taking medicine and taboos, but in fact, when taking western medicine, it is also necessary to pay attention to dietary taboos.

Taking western medicine still needs to be taboo (Xi Ruonan/People’s Network)

Oral drugs enter the body through absorption (through gastrointestinal tract), distribution (through blood and lymph), metabolism (through liver) and excretion (through kidney and biliary tract). Some foods may affect the absorption, metabolism and other processes of drugs, reduce the efficacy, even make drugs ineffective, and even increase the toxicity of drugs in severe cases. Therefore, according to the condition and treatment needs, patients should follow the doctor’s advice and avoid certain foods when taking medicine, so as not to affect the curative effect of drugs or increase the adverse reactions of drugs. Here are some foods that need to be avoided when taking medicine.

Which drugs should not be taken with grapefruit juice?

Grapefruit juice contains a component that inhibits drug metabolizing enzymes-furan coumarin. It can double the efficacy of drugs entering the blood, thus changing the "therapeutic dose" into "toxic dose". When the situation is serious, users may have adverse reactions such as gastrointestinal bleeding, acute renal failure, respiratory failure and sudden death. In addition, organic anion transport polypeptide OATP1A2 can transport drugs from small intestine to blood, whileNaringin contained in citrus fruits can hinder it. Specifically, the following drugs should not be taken with grapefruit juice:

Antihypertensive drugs (amlodipine, felodipine, nifedipine)

Cholesterol lowering drugs (atorvastatin, lovastatin, simvastatin, fluvastatin, pravastatin)

Hypoglycemic drugs (repaglinide, glibenclamide)

Antiarrhythmic drugs (amiodarone, verapamil)

Antiplatelet drugs (clopidogrel, cilostazol, aspirin, warfarin)

Tetracyclines (erythromycin, clarithromycin)

Antidepressants (trazodone, sertraline)

Antipsychotics (quetiapine, clozapine, haloperidol)

Antiepileptic drugs (carbamazepine)

Sedative hypnotics (triazolam, midazolam, buspirone, diazepam, clonazepam, zolpidem)

Analgesics (methadone, oxycodone, fentanyl)

Medicine for improving cerebral circulation (nimodipine)

Gastrointestinal drugs (cisapride, domperidone)

Cough suppressant (dextromethorphan)

Vasoconstrictor (ergotamine)

Uterine contraction and induced labor drug (mifepristone)

Immunosuppressive drugs after organ transplantation (cyclosporine, tacrolimus)

Antitumor drugs (cyclophosphamide, dasatinib)

Antierectile dysfunction drugs (tadanafil, vardenafil)

Which drugs should not be taken with ethanol?

The combination of ethanol in alcohol and cephalosporins can cause acetaldehyde poisoning. The combination of ethanol and cardiovascular drugs will inhibit the contractility of sympathetic nerve and myocardium, enhance the effect of antihypertensive drugs, reduce blood pressure sharply, and endanger health. The combination of ethanol and hypoglycemic drugs can increase insulin secretion, enhance the effect of hypoglycemic drugs and trigger hypoglycemia shock. The combination of ethanol and sedatives can inhibit the patient’s breathing and lead to coma. The combination of ethanol and anti-gout drugs will weaken the efficacy of drugs in inhibiting uric acid production. The combination of ethanol and antipyretic and analgesic drugs will stimulate gastrointestinal mucosa and cause gastrointestinal bleeding. As an enzyme inducer of liver drugs, ethanol combined with anti-tuberculosis drugs and anti-tumor drugs will accelerate drug metabolism and increase hepatotoxicity. Specifically, the following drugs should not be taken with alcohol:

Antibiotics (cephalosporins, ornidazole, metronidazole, furazolidone, chloramphenicol)

Antihypertensive drugs (reserpine, captopril, nifedipine, hydralazine)

Diuretics (furosemide, spironolactone, hydrochlorothiazide)

Antiangina drugs (nitroglycerin, isosorbide dinitrate)

Cardiotonic drugs (digitalis, digoxin)

Hypoglycemic drugs (gliclazide, glibenclamide, gliquidone, phenformin)

Antiepileptic drugs (carbamazepine, phenytoin sodium)

Sedative hypnotics (diazepam, phenobarbital, chlorzoxazole)

Antidepressants (imipramine, amitriptyline)

Antihistamines (chlorphenamine, cyproheptadine, diphenhydramine)

Antipsychotics (perphenazine, chlorpromazine)

Antigout drugs (allopurinol)

Antipyretic and analgesic drugs (ibuprofen, aspirin, acetaminophen, indomethacin)

Anti-tuberculosis drugs (rifampicin, isoniazid, ethambutol, pyrazinamide)

Gastric acid secretion inhibitor (cimetidine)

Antitumor drugs (fluorouracil, methotrexate)

Which drugs should be taken with milk and yogurt?

Milk and yogurt contain more calcium, protein, amino acids, tyramine and other ingredients. Calcium ions can form insoluble complexes with antibiotics, iron agents, metal ions and other drugs in the intestine, which will affect the absorption of drugs and lead to weakened curative effect. Aromatic amino acids in milk will significantly reduce the absorption of anti-Parkinson’s drugs. Monoamine oxidase inhibitors can accumulate.Tyramine in milk causes adverse reactions such as sudden rise of blood pressure and arrhythmia. Protein in milk can reduce the efficacy of theophylline drugs. Specifically, the following drugs should not be taken with milk and yogurt:

Antibiotics (tetracycline, doxycycline, minocycline, moxifloxacin, levofloxacin)

Gastric mucosal protective drugs (aluminum hydroxide, magnesium aluminum carbonate, colloidal bismuth pectin)

Osteoporosis drugs (alendronate sodium, ibandronate sodium)

Anti-Parkinson drugs (levodopa, carbidopa)

Antihypothyroid drug (levothyroxine sodium)

Iron supplement (ferrous succinate)

Antiasthmatic drugs (theophylline, aminophylline)

Medicine for treat constipation (bisacodyl)

Monoamine oxidase inhibitors (selegiline, isoniazid)

Which drugs should not be taken with tea and coffee?

Tea and coffee contain caffeine, theophylline and other alkaloids, which can excite the central nervous system and reduce the sleeping effect of sedative and hypnotic drugs. Tannin contained in tea can combine with protein to form tannic acid protein, which inactivates probiotics with enzyme activity, weakens the effect of digestive aid or invalidates the drug. Tannin combined with antibiotics will affect antibacterial activity, and antibiotics can inhibit theophylline metabolism, increase theophylline toxicity, and lead to adverse reactions such as nausea and vomiting. Tannin can also precipitate with metal ions, reducing the efficacy of drugs such as iron and calcium. Tannin combined with cardiac glycosides and alkaloids will form insoluble precipitate, which will hinder gastrointestinal absorption and affect the efficacy of drugs. Specifically, the following drugs should not be taken with tea and coffee:

Digestive AIDS (multi-enzyme tablets, pancreatin tablets, mother-feeding students, lactase students)

Cardiotonic (digoxin)

Iron supplement (ferrous succinate)

Calcium supplements (calcium carbonate, calcium gluconate)

Sedative hypnotics (diazepam, phenobarbital, zopiclone)

Gastric mucosal protective drugs (bismuth potassium citrate, sucralfate)

Antibiotics (minocycline, doxycycline, roxithromycin, azithromycin)

Alkaloids (codeine, atropine, ephedrine)

Which drugs should not be taken with polycyclic aromatic hydrocarbons (nicotine)?

Nicotine, nicotine and other components contained in tobacco can affect the metabolism of antiasthmatic drugs, hypoglycemic drugs, diuretics, anti-angina drugs and other drugs, leading to the decrease of drug concentration in blood and the increase of excretion rate, thus affecting the curative effect of drugs. Nicotine in tobacco can excite the central nervous system, reduce the sensitivity of the body to sedative and analgesic drugs, and make the efficacy of drugs worse. Smoking will increase the secretion of gastric acid and pepsin, stimulate vasoconstriction, delay gastric emptying, and affect the protective effect of gastric mucosa on drugs. Long-term smokers will form a layer of smoke tar on the inner membrane of trachea. If patients need to use aerosol for treatment, smoke tar will affect the effect of aerosol in treatment. In addition, smoking will also weaken the role of local anesthetics and increase the chance of pain after anesthesia. Specifically, the following drugs should not be taken with polycyclic aromatic hydrocarbons (nicotine):

Antiasthmatic drugs (theophylline, aminophylline)

Hypoglycemic drugs (insulin, tolbutamide, phenformin)

Antiangina drugs (nifedipine, atenolol)

Gastric acid secretion inhibitors (cimetidine, ranitidine)

Diuretics (furosemide)

Antipyretic analgesic (acetaminophen)

Antipsychotics (clozapine)

Sedative hypnotics (diazepam, azone)

Local anesthetic (lidocaine)

All kinds of aerosols (salbutamol)

Which drugs should not be taken with foods containing potassium?

Banana, citrus, coriander, laver, spinach and other foods with high potassium content should not be combined with drugs such as spironolactone, triamcinolone acetonide and potassium chloride to avoid hyperkalemia.

Which drugs should not be taken with pickled food?

Drugs containing aminopyrine, such as acetaminophen, aminopyrine caffeine and compound amantadine aminopyrine, and sodium nitrite in pickled food can form carcinogenic nitroso compounds in gastric acid. Therefore, drugs containing aminopyrine can not be eaten with pickled food.

Which drugs should not be taken with high-protein foods?

When high-protein food is combined with levodopa, it will produce a large number of amino acids in the intestine that hinder the absorption of drugs, which will reduce the efficacy of drugs. In addition, when high-protein food is combined with isoniazid, tyramine, an intermediate product of protein decomposition, can accumulate in the body, causing patients to have symptoms such as headache, palpitation, limb swelling and numbness. (Jin Tang)

This article is scientifically checked by Zhang Jianping, deputy director of Pharmacy Department of the Sixth People’s Hospital affiliated to Shanghai Jiaotong University.

Contributed by "reaching the doctor and caring for him"

　　Xinhua News Agency, Wuhan, May 22nd Question: Why did the "three noes" aphrodisiac become the "explosion" of the network? — — Starting from the inter-provincial manufacturing and selling fake health care products chain

　　Xinhua News Agency reporter Jianqiang Liang

　　Several handfuls of sildenafil powder and several handfuls of corn flour are mixed and stirred in the washbasin, and then put into capsules. The exquisite packaging box is grandly marked with the functions of "strengthening yang" and "tonifying kidney deficiency" — — In this way, "health products" without formal manufacturers, accurate production dates and relevant quality tests have been sold to more than 20 provinces through the Internet.

　　Why can the "three no health products" processed in small workshops sell well or even become "explosions" on the network platform? The reporter conducted an investigation.

　　A batch of online shopping low-priced health care products led to a major case of selling fakes.

　　In February this year, Mr. Li, who intends to open a health care product store, purchased a batch of goods from the online platform. After the arrival of the goods, some of the health care products aroused his suspicion.

　　"I may have bought some fakes online." Mr. Li chose to call the police. The police sent these suspicious products with the words "quick-acting aphrodisiac" printed on the boxes to the food and drug supervision and administration department for testing. The test found that there were no formal manufacturers of many products submitted for inspection, belonging to "three noes" counterfeit drugs, and sildenafil commonly known as "Viagra" was illegally added.

　　How did such "health products" enter the market?

　　The public security organs traced it and found that these counterfeit drugs were purchased from a shop in a group shopping APP — — "Heroes Paradise" is owned by Wang, a native of Shandong. After on-the-spot investigation, the police locked a two-story building suspected of being a warehouse and delivery den.

　　Recently, the police successfully arrested Wang after continuous investigation and control.

　　The police of the task force involved in handling the case revealed that when the police entered the building, the staff were still busy counting and packing the goods to be sent. In the room, there are huge cartons containing thousands of boxes of different kinds of "health products" such as "tiger tiger gives birth to power". On the second floor, there are many computers, and the customer service staff are busy answering customer inquiries, filling out express orders, printing invoices and so on.

　　Three places form a chain of manufacturing and selling fake goods.

　　Where does the "three noes" fake medicine come from? The task force tracked and found that a chain of counterfeiting and selling fakes involving Hubei, Henan and Shandong has been formed.

　　The police tracked down and found that a batch of sildenafil was transported from Wuhan to Zhengzhou. In a fake den, the case-handling personnel arrested Wang Momin, who was suspected of making fake drugs, and seized more than 10,000 semi-finished fake drug capsules.

　　According to Wang Momin’s confession, since May 2017, she has organized and produced more than 10 kinds of "health products" such as Deer Whip Pill, Flower Picker, American Panther and Tiger Tiger Tiger, but it does not have the production qualification related to food and medicine.

　　Wang Momin bought 75 kilograms of sildenafil powder from Wuhan at a price of 10,000 yuan per 25 kilograms. There is no standard in the production process, the site has not been disinfected, and the dosage of sildenafil is also very random.

　　"Usually, a few handfuls of sildenafil powder and a few handfuls of corn flour are poured into the washbasin, stirred, scooped with capsules and covered, and it is made." Wang Momin confessed, "Corn flour is bought from the vegetable market in Zhengzhou, and how much sildenafil is put depends on estimation."

　　The cost of a box of "health products" produced in this way is only a few cents, but the price in the network ranges from more than ten yuan to dozens of yuan.

　　According to the investigators, although the "health products" produced by this den have different packaging, the ingredients are actually exactly the same. In the instructions of some products, it is claimed that "patients with heart disease and hypertension can take it", but in fact, for people with cardiovascular diseases, improper use of sildenafil is easy to cause harm to the body, and excessive dosage may even lead to sudden death.

　　The police initially estimated that the sildenafil purchased by Wang Momin was enough to produce millions of counterfeit drugs.

　　80,000 yuan "swipe" has become a network "explosion"

　　In Hubei, the police locked the source of sildenafil; At Wang Momin’s production den in Zhengzhou, the police seized more than 10,000 semi-finished counterfeit capsules; In addition, the police in Zhaoyuan, Shandong Province seized more than 100,000 counterfeit drugs from the sales warehouse of Wang, who sold the products. The total value involved is expected to exceed 5 million yuan.

　　Why can the "three no health products" processed in small workshops sell well in the network platform? The reporter’s investigation found that the online "brushing" makes the sales volume "virtual high", which is one of the important ways for criminal suspects to attract business.

　　Police investigation found that in 2017, Wang opened a number of online stores on Pinduoduo. Subsequently, he put on the shelves a variety of "health products" such as "Tiger Tiger gives birth to power" and "German Black King Kong". In order to allow more customers to see their own shops when searching, he has invested nearly 80,000 yuan to "swipe the bill" and turned the goods into "explosions".

　　With the help of "brushing" to forge sales, Wang’s business has improved significantly. Taking January this year as an example, Wang sold more than 6,000 counterfeit drugs.

　　Relevant sales records show that since Wang opened an online store, various "health products" have been sold to more than 20 provinces. After the abnormal business conditions such as "brushing the bill" were discovered by the online platform, Wang was fined 77,000 yuan.

　　Shang Zhongsheng, an expert on social issues and deputy director of the Research Center for Urban Security and Social Management of Wuhan University, believes that cross-provincial counterfeiting and sales have formed a chain and become an "explosion" in the network, indicating that there are omissions at the regulatory level. "On the one hand, relevant departments such as industry and commerce, food and drug supervision, and public security need to strengthen linkage and form a joint force; On the other hand, we should also intensify our efforts to crack down on the found acts of counterfeiting and selling fake goods. You can’t just stare at offline physical stores, but also pay more attention to online sales. "

　　"As a platform for online sales, we must put ‘ Access ’ For related stores involving drugs and health products, the relevant qualifications should be strictly reviewed. " Shang Zhongsheng said that the punishment should be more shocking for shops that found violations of laws and regulations such as "brushing bills" and selling fakes.

　　Xinhua News Agency, United Nations, July 20th (Reporter Ni Hongmei, Shi Xiaomeng) The United Nations Security Council unanimously adopted a resolution on the 20th, reaffirming a series of sanctions against extremist organizations "Islamic State" and "Al Qaeda", and adding eight groups and individuals to the sanctions list. Liu Jieyi, Permanent Representative of China to the United Nations, presided over the relevant meeting.

　　The resolution reiterated that countries should impose sanctions such as asset freeze, travel ban and arms embargo on the Islamic State, Al Qaeda and related groups and individuals. The resolution adjusted the details of the sanctions measures according to the changes in the activities of extremist organizations.

　　The resolution also added two extremist organizations, two currency trading companies and four individuals operating in Syria to the sanctions list, arguing that they are related to the activities of the "Islamic State" and "Al Qaeda" and should be sanctioned.

　　Liu Jieyi said after the adoption of the resolution that China welcomes the unanimous adoption of the resolution by the Security Council. Terrorism is the public enemy of all mankind. China supports the coordinated actions of the international community and the comprehensive use of effective means to strengthen anti-terrorism cooperation, especially to strengthen the response to new challenges such as terrorists using the Internet to spread, incite, organize terrorist activities, financing terrorism and the return of foreign terrorist fighters. Anti-terrorism actions must adhere to unified standards, give full play to the leading role of the United Nations and the Security Council, and strengthen effective coordination.

　　Liu Jieyi said that the 1267 Committee is an important anti-terrorism mechanism of the United Nations and the Security Council. China supports the 1267 Committee to maintain close communication with the countries concerned, strengthen cooperation with regional and sub-regional counter-terrorism mechanisms, continuously improve its work efficiency and make greater contributions to the international counter-terrorism cause. It is hoped that the vast number of Member States and the Secretariat will strictly abide by the relevant resolutions and the rules of procedure of the Committee, continue to support and cooperate with the work of the Committee, and jointly safeguard the authority and effectiveness of the sanctions mechanism.

　　In 1999, the Security Council adopted resolution 1267, and established the 1267 Committee, a sanctions agency specifically targeting al-Qaeda and the Taliban and related entities and individuals. In December 2015, the Security Council passed a resolution to include individuals and entities supporting the "Islamic State" within the scope of sanctions. The 1267 Committee is therefore called the "Islamic State" and "Al Qaeda" sanctions committee.